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Hydrocodone



Brand Name: Examples Reprexain and Vicoprofen



Hydrocodone/Ibuprofen is used for:

Short-term treatment of pain. Hydrocodone/Ibuprofen is an opioid analgesic and NSAID combination. Exactly how it works is not known. Ibuprofen may block certain substances in the body that cause inflammation. Hydrocodone may affect opiate receptors in the brain to decrease pain.

Before using Hydrocodone/Ibuprofen:

Some medical conditions may interact with Hydrocodone/Ibuprofen. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you: if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you or a family member has a history of mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse, or if you drink alcohol if you have a history of kidney, liver, or lung problems, diabetes, or stomach or bowel problems (eg, bleeding, perforation, ulcers) if you have a history of swelling or fluid buildup, lupus, asthma, growths in the nose (nasal polyps), or mouth inflammation if you have high blood pressure, blood disorders, bleeding or clotting problems, heart problems (eg, heart failure), or blood vessel problems, or if you are at risk for any of these problems if you have Addison disease, thyroid problems, an enlarged prostate, or trouble urinating if you have asthma or breathing problems, seizures, growths in the brain, a recent head injury, or if you have had recent surgery if you have poor health, dehydration or low fluid volume, or low blood sodium levels Some MEDICINES MAY INTERACT with Hydrocodone/Ibuprofen. Tell your health care provider if you are taking any other medicines, especially any of the following: Anticoagulants (eg, warfarin), corticosteroids (eg, prednisone), heparin, salicylates (eg, aspirin), or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because the risk of bleeding, including stomach bleeding, may be increased Antihistamines (eg, diphenhydramine), barbiturates (eg, phenobarbital), cimetidine, narcotic pain medicine (eg, codeine), or sodium oxybate (GHB) because the risk of excessive drowsiness or severe breathing problems may be increased Anticholinergics (eg, benztropine), MAOIs (eg, phenelzine), probenecid, or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Hydrocodone/Ibuprofen's side effects Naltrexone or rifampin because they may decrease Hydrocodone/Ibuprofen's effectiveness Cyclosporine, lithium, methotrexate, or quinolones (eg, ciprofloxacin) because the risk of their side effects may be increased by Hydrocodone/Ibuprofen Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Hydrocodone/Ibuprofen This may not be a complete list of all interactions that may occur. Ask your health care provider if Hydrocodone/Ibuprofen may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Hydrocodone/Ibuprofen:

Use Hydrocodone/Ibuprofen as directed by your doctor. Check the label on the medicine for exact dosing instructions. Hydrocodone/Ibuprofen comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Hydrocodone/Ibuprofen refilled. Take Hydrocodone/Ibuprofen by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation. If you miss a dose of Hydrocodone/Ibuprofen and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use Hydrocodone/Ibuprofen.

Possible side effects of Hydrocodone/Ibuprofen:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome: Anxiety; constipation; diarrhea; dizziness; dry mouth; gas; headache; heartburn; increased sweating; loss of appetite; nausea; nervousness; stomach pain or upset; trouble sleeping; vomiting; weakness. Seek medical attention right away if any of these SEVERE side effects occur: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody, black, or tarry stools; blurred vision; change in the amount of urine produced; chest pain; confusion; dark urine; depression; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; mental or mood changes; numbness of an arm or leg; one-sided weakness; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe headache or dizziness; severe or persistent stomach pain or nausea; severe vomiting; shortness of breath; slow or shallow breathing; stiff neck; sudden or unexplained weight gain; swelling of hands, legs, or feet; unusual bruising or bleeding; unusual joint or muscle pain; unusual tiredness or weakness; vision or speech changes; vomit that looks like coffee grounds; yellowing of the skin or eyes. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at _ttp://www.fda.gov/medwatch.

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