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Bupropion



Brand Name: Wellbutrin



Bupropion is used for:

Treating depression. It may also be used for other conditions as determined by your doctor. Bupropion is an antidepressant. It works in the brain to treat depression. Exactly how it works is not known.

Before using Bupropion:

Some medical conditions may interact with Bupropion. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you: if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you or a family member has a history of bipolar disorder (manic depression), other mental or mood problems (eg, depression), suicidal thoughts or attempts, or alcohol or substance abuse if you have diabetes, kidney problems, liver problems (eg, cirrhosis), high blood pressure, heart problems (eg, congestive heart failure), or a recent heart attack if you have a history of seizures, head injury, or tumor in the brain or spinal cord Some MEDICINES MAY INTERACT with Bupropion. Tell your health care provider if you are taking any other medicines, especially any of the following: Amantadine, antipsychotics (eg, haloperidol, risperidone), corticosteroids (eg, prednisone), cyclophosphamide, efavirenz, HIV protease inhibitors (eg, nelfinavir, ritonavir), insulin, levodopa, MAOIs (eg, phenelzine), nicotine patches, oral hypoglycemics (eg, glipizide), orphenadrine, other antidepressants (eg, amitriptyline, fluoxetine), sympathomimetics (eg, pseudoephedrine), theophylline, thiotepa, or tiagabine because they may increase the risk of Bupropion's side effects Carbamazepine, phenobarbital, phenytoin, or rifampin because they may decrease Bupropion's effectiveness Antiarrhythmics (eg, flecainide, propafenone), beta-blockers (eg, metoprolol), phenothiazines (eg, thioridazine), selective serotonin reuptake inhibitor (SSRI) antidepressants (eg, fluoxetine), or tricyclic antidepressants (eg, nortriptyline) because the risk of their side effects may be increased by Bupropion This may not be a complete list of all interactions that may occur. Ask your health care provider if Bupropion may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Bupropion:

Use Bupropion as directed by your doctor. Check the label on the medicine for exact dosing instructions. Bupropion comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Bupropion refilled. Take Bupropion by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation. Several weeks may pass before your symptoms improve. Do not stop taking Bupropion without checking with your doctor. Take your doses at the same times each day, at least 6 hours apart unless directed otherwise by your doctor. This may help to decrease the risk of seizures with Bupropion. Continue to take Bupropion even if you feel well. Do not miss any doses. If you miss a dose of Bupropion, skip the missed dose and go back to your regular dosing schedule. Do not take more than 1 dose within 6 hours. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use Bupropion.

Possible side effects of Bupropion:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome: Changes in appetite; constipation; dizziness; drowsiness; dry mouth; headache; increased sweating; nausea; nervousness; restlessness; taste changes; trouble sleeping; vomiting; weight changes. Seek medical attention right away if any of these SEVERE side effects occur: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue, unusual hoarseness); blurred vision or other vision changes; changes in sexual desire or ability; chest pain; confusion; dark urine; delusions; fainting; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; hearing problems; menstrual changes; new or worsening mental or mood changes (eg, concentration problems, depression, panic attacks, aggressiveness, agitation, anxiety, impulsiveness, irritability, hostility, exaggerated feeling of well-being, inability to sit still); red, swollen, blistered, or peeling skin; seizures; severe headache or dizziness; severe or persistent joint or muscle pain; severe or persistent nausea, vomiting, or stomach pain; severe or persistent nervousness, restlessness, or trouble sleeping; shortness of breath; suicidal thoughts or attempts; tremor; unusual swelling; yellowing of the skin or eyes. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at _ttp://www.fda.gov/medwatch.

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