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Lithium



Brand Name: Eskalith



Lithium is used for:

Treating manic episodes in patients with bipolar disorder. It is also used to reduce the frequency and decrease the severity of manic episodes in patients with bipolar disorder. It may also be used for other conditions as determined by your doctor. Lithium is an antimanic agent. Exactly how Lithium works is unknown, but it may work by altering the balance of certain chemicals in the brain.

Before using Lithium:

Some medical conditions may interact with Lithium. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you: if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you have diarrhea, vomiting, excessive sweating, dehydration, fever, infection, or illness, or you are in a weakened state if you have kidney, heart, blood vessel, or thyroid problems if you have brain or nerve problems (eg, organic brain syndrome) if you are on a low-salt diet Some MEDICINES MAY INTERACT with Lithium. Tell your health care provider if you are taking any other medicines, especially any of the following: Acetazolamide, urea, urinary alkalinizers (eg, sodium bicarbonate), or xanthines (eg, theophylline) because they may decrease Lithium's effectiveness ACE inhibitors (eg, enalapril), angiotensin II receptor antagonists (eg, losartan), calcium channel blockers (eg, verapamil), carbamazepine, diuretics (eg, furosemide, hydrochlorothiazide), hydantoins (eg, phenytoin), methyldopa, metronidazole, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin, celecoxib), or selective serotonin reuptake inhibitor (SSRI) antidepressants (eg, fluoxetine) because the risk of toxicity of Lithium may be increased Butyrophenones (eg, haloperidol) or other medicines for mental or mood problems because the risk of serious side effects, such as confusion, involuntary muscle movements, fever, and brain damage, may be increased Iodide preparations (eg, potassium iodide) because the risk of low thyroid levels may be increased Nondepolarizing neuromuscular blockers (eg, vecuronium) or succinylcholine because the risk of their side effects may be increased by Lithium This may not be a complete list of all interactions that may occur. Ask your health care provider if Lithium may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lithium:

Use Lithium as directed by your doctor. Check the label on the medicine for exact dosing instructions. Take Lithium by mouth after meals or with food or milk to decrease stomach upset. Drinking extra fluids while you are taking Lithium is recommended. Check with your doctor for instructions. Do not change your diet, including the amount of salt in your diet, unless instructed by your doctor. If you miss a dose of Lithium, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use Lithium.

Possible side effects of Lithium:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome: Mild hand tremor; mild thirst; temporary, mild nausea and general discomfort at the beginning of treatment. Seek medical attention right away if any of these SEVERE side effects occur: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; confusion; diarrhea; drowsiness; excessive weight gain; fainting; giddiness; inability to control the bladder or bowels; increased thirst; increased or decreased urination; involuntary twitching or muscle movements; loss of consciousness; loss of coordination; muscle weakness; persistent headache; persistent or severe nausea; ringing in the ears; seizures; slow or irregular heartbeat; slurred speech; swelling of the ankles or wrists; unsteadiness; vision changes; vomiting. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at _ttp://www.fda.gov/medwatch.